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Last updated: 2016/12/4
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LATS2 monoclonal antibody, clone ST-3D10

  • Catalog # : MAB0019
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against LATS2.
  • Immunogen:
  • GST-Lats2N, corresponding N-terminus portion of human Lats2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Human Lats2 Monoclonal Antibody detects human Lats2 by western blotting and IP-western blotting.
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunoprecipitation (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM HEPES/KOH, 150 mM NaCl, pH 7.5 (50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Immunoprecipitation
  • Immunoprecipitation
  • IP-Western blot analysis of human LATS2 using HeLa cell extract.
    IP antibody using MAB0019 (Lane 1), MAB0009 (Lane 2) and Isotype Control (Lane 3).
    Western blot antibody using LATS2 monoclonal antibody, clone ST-3D10 (Cat # MAB0019).
  • Application Image
  • Western Blot (Cell lysate)
  • Gene Information
  • Gene Name:
  • LATS2
  • Gene Alias:
  • FLJ13161,KPM
  • Gene Description:
  • LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Gene Summary:
  • This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq
  • Other Designations:
  • LATS (large tumor suppressor, Drosophila) homolog 2,LATS, large tumor suppressor, homolog 2,OTTHUMP00000018106,kinase phosphorylated during mitosis protein,serine/threonine kinase KPM,warts-like kinase
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