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Last updated: 2016/10/23
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LATS2 (phospho S83) monoclonal antibody, clone ST-3B11

  • Catalog # : MAB0009
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic phosphopeptide of LATS2.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S83 of human LATS2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Quality Control Testing:
  • Phospho-LATS2 Ser83 Antibody detects phosphorylated recombinat LATS2 only when phosphorylated at serine83, by western blotting.
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    ELISA (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM HEPES/KOH, 150 mM NaCl, pH 7.5 (50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • ELISA for measurement of recombinant Aurora A kinase activity using LATS2 (phospho S83) monoclonal antibody, clone ST-3B11 (Cat # MAB0009).
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • LATS2
  • Gene Alias:
  • FLJ13161,KPM
  • Gene Description:
  • LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Gene Summary:
  • This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq
  • Other Designations:
  • LATS (large tumor suppressor, Drosophila) homolog 2,LATS, large tumor suppressor, homolog 2,OTTHUMP00000018106,kinase phosphorylated during mitosis protein,serine/threonine kinase KPM,warts-like kinase
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