Anti-Ustekinumab (Human) ELISA Kit (Qualitative)
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Specification
Product Description
Ustekinumab (Human) ELISA Kit (Qualitative) is a qualitative determination of antibodies to ustekinumab in serum and plasma.
Assay Type
Qualitative
Reactivity
Human
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — IL12A
Entrez GeneID
3592Gene Name
IL12A
Gene Alias
CLMF, IL-12A, NFSK, NKSF1, P35
Gene Description
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Omim ID
161560Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq
Other Designations
IL-12, subunit p35|NF cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|interleukin 12, p35|interleukin 12A|interleukin-12 alpha chain|natural killer cell stimulatory factor 1, 35 kD subunit
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Gene Info — IL23A
Entrez GeneID
51561Gene Name
IL23A
Gene Alias
IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF
Gene Description
interleukin 23, alpha subunit p19
Omim ID
605580Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq
Other Designations
JKA3 induced upon T-cell activation|interleukin 23 p19 subunit
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