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Last updated: 2022/8/14

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HPGD Inhibitor Screening Kit (Fluorometric) 

  • Catalog # : KA6479
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  • Specification
  • Product Description:
  • HPGD Inhibitor Screening Kit (Fluorometric) offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of 15-PGDH inhibitors.
  • Storage Instruction:
  • Store the kit at -20°C.
    Avoid repeated freezing and thawing.
  • Detection Method:
  • Fluorescence (Ex/Em = 535/587 nm)
  • Applications
  • Inhibition Assay
  • Inhibition of 15-PGDH Activity by 15-PGDH Inhibitor Control. IC50 was determined to be 9.1 +/- 0.1 nM.
  • Application Image
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 3248
  • Gene Name:
  • HPGD
  • Gene Alias:
  • 15-PGDH,PGDH,PGDH1,SDR36C1
  • Gene Description:
  • hydroxyprostaglandin dehydrogenase 15-(NAD)
  • Gene Summary:
  • This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 15-hydroxy prostaglandin dehydrogenase,15-hydroxyprostaglandin dehydrogenase,NAD+-dependent 15-hydroxyprostaglandin dehydrogenase,short chain dehydrogenase/reductase family 36C, member 1
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