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Last updated: 2022/8/14

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AHCY Inhibitor Screening Kit (Fluorometric) 

  • Catalog # : KA6472
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  • Specification
  • Product Description:
  • AHCY Inhibitor Screening Kit (Fluorometric) the homocysteine generated from the breakdown of SAH is measured using a Thiol Detecting Reagent resulting in enhanced fluorescence which is measured at Ex/Em = 392/482 nm.
  • Storage Instruction:
  • Store the kit at -20°C.
    Avoid repeated freezing and thawing.
  • Detection Method:
  • Fluorescence (Ex/Em = 392/482 nm)
  • Applications
  • Inhibition Assay
  • Inhibition of AHCY Enzyme activity by 3-Deazaneplanocin A. IC50 of 3-Deazaneplanocin A was determined to be 0.137 nM.
  • Application Image
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 191
  • Gene Name:
  • AHCY
  • Gene Alias:
  • SAHH
  • Gene Description:
  • S-adenosylhomocysteine hydrolase
  • Gene Summary:
  • S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030684,adenosylhomocysteinase
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