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Last updated: 2022/8/14

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ACE2 Inhibitor Screening Kit 

  • Catalog # : KA6470
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  • Specification
  • Product Description:
  • ACE2 Inhibitor Screening Kit can be used to screen for potent inhibitors of ACE2 activity.
  • Storage Instruction:
  • Store the kit at -20°C.
    Avoid repeated freezing and thawing.
  • Detection Method:
  • Fluorescence (Ex/Em = 320/420 nm)
  • Applications
  • Inhibition Assay
  • Inhibition of ACE2 activity by ACE2 Inhibitor, IC50 = 33.0 ± 0.6 nM (n = 3).
  • Application Image
  • Inhibition Assay
  • Gene Information
  • Gene Name:
  • ACE2
  • Gene Alias:
  • ACEH,DKFZp434A014
  • Gene Description:
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • Gene Summary:
  • The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
  • Other Designations:
  • ACE-related carboxypeptidase,OTTHUMP00000022963,angiotensin I converting enzyme 2,angiotensin converting enzyme-like protein
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