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Last updated: 2022/8/14

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F10 Inhibitor Screening Kit (Fluorometric) 

  • Catalog # : KA6454
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  • Specification
  • Product Description:
  • F10 Inhibitor Screening Kit (Fluorometric) is used for screening potential inhibitors of Factor Xa.
  • Storage Instruction:
  • Store at -20°C, protected from light.
    Aliquot to avoid repeated freezing and thawing.
  • Excitation/
    Emission (nm):
  • 350nm/450nm
  • Applications
  • Inhibition Assay
  • Inhibition Assay
  • Inhibition of F10 activity by F10 inhibitor.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2159
  • Gene Name:
  • F10
  • Gene Alias:
  • FX,FXA
  • Gene Description:
  • coagulation factor X
  • Gene Summary:
  • This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018735,Stuart-Prower factor,factor Xa,prothrombinase
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