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Last updated: 2022/8/14

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CTSL1 Inhibitor Screening Kit (Fluorometric) 

  • Catalog # : KA6449
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  • Specification
  • Product Description:
  • CTSL1 Inhibitor Screening Kit (Fluorometric) is used for screening potential inhibitors of Cathepsin L.
  • Storage Instruction:
  • Store at -80°C, protected from light.
    Aliquot to avoid repeated freezing and thawing.
  • Excitation/
    Emission (nm):
  • 400nm/505nm
  • Applications
  • Inhibition Assay
  • Inhibition Assay
  • Inhibition of Cathepsin L activity by CTSL inhibitor.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1514
  • Gene Name:
  • CTSL1
  • Gene Alias:
  • CATL,CTSL,FLJ31037,MEP
  • Gene Description:
  • cathepsin L1
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021601,OTTHUMP00000021602,OTTHUMP00000063566,cathepsin L,major excreted protein
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