Anti-Vedolizumab (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for the qualitative measurement of antibody against Vedolizumab in human serum and plasma. Target gene is integrin a4b7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7).
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq
Other Designations:
269C wild type,antigen CD49D, alpha-4 subunit of VLA-4 receptor,integrin alpha 4,integrin alpha-4 subunit,very late activation protein 4 receptor, alpha 4 subunit