SIGLEC5 (Human) ELISA Kit
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
SIGLEC5 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for the quantitative measurement of human SIGLEC5 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Suitable Sample
Cell Culture supernatants, Cell Lysates, Plasma (EDTA, Heparin) and Serum.
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
46.9 to 3000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — SIGLEC5
Entrez GeneID
8778Protein Accession#
O15389Gene Name
SIGLEC5
Gene Alias
CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Gene Description
sialic acid binding Ig-like lectin 5
Omim ID
604200Gene Ontology
HyperlinkGene Summary
The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]).[supplied by OMIM
Other Designations
CD33 antigen-like 2|OB binding protein-2|sialic acid-binding immunoglobulin-like lectin 5
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