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TDP1 (Human) ELISA Kit 

  • Catalog # : KA6122
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  • Specification
  • Product Description:
  • TDP1 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human TDP1 in Serum, Plasma and Cell Culture.
  • Calibration Range:
  • 1.563 to 100 ng/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA6122
    The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Serum, Plasma, Cell Culture
  • Sample Volume:
  • 50 uL
  • Label:
  • Peroxidase-conjugated
  • Detection Method:
  • Colorimetric
  • Regulatory Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Gene Name:
  • TDP1
  • Gene Alias:
  • FLJ11090,MGC104252
  • Gene Description:
  • tyrosyl-DNA phosphodiesterase 1
  • Gene Summary:
  • The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq
  • Other Designations:
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