Factor VIIa (Human) Chromogenic Activity Assay Kit
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Factor VIIa (Human) Chromogenic Activity Assay Kit is developed to determine FVIIa activity in human plasma, serum, and cell culture samples. This assay couples immunofunctional and indirect amidolytic function.
Suitable Sample
Cell Culture Supernatants, Plasma and Serum.
Sample Volume
100 uL
Calibration Range
0.438 to 28 AU/mL or 7.813 to 500 ng/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
-
Applications
Functional Study
-
Gene Info — F7
Entrez GeneID
2155Protein Accession#
P08709Gene Name
F7
Gene Alias
-
Gene Description
coagulation factor VII (serum prothrombin conversion accelerator)
Omim ID
227500Gene Ontology
HyperlinkGene Summary
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq
Other Designations
FVII coagulation protein|OTTHUMP00000018733|OTTHUMP00000018734|coagulation factor VII|eptacog alfa
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com