MRC1 (Human) ELISA Kit
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Specification
Product Description
MRC1 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human MRC1 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
Suitable Sample
Cell culture supernates, serum and plasma (heparin, EDTA, citrate)
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.78 to 50 ng/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for six months. For long term storage store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Quantification
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Gene Info — MRC1
Entrez GeneID
4360Protein Accession#
P22897Gene Name
MRC1
Gene Alias
CD206, CLEC13D, MMR
Gene Description
mannose receptor, C type 1
Omim ID
153618Gene Ontology
HyperlinkGene Summary
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq
Other Designations
OTTHUMP00000019245|OTTHUMP00000045206|macrophage mannose receptor|mannose receptor C type 1
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