TIMP1 (Human) ELISA Kit
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Specification
Product Description
TIMP1 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human TIMP1 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.
Suitable Sample
Cell culture supernates, serum, plasma (heparin, EDTA) and saliva
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
156 to 10000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — TIMP1
Entrez GeneID
7076Gene Name
TIMP1
Gene Alias
CLGI, EPA, EPO, FLJ90373, HCI, TIMP
Gene Description
TIMP metallopeptidase inhibitor 1
Omim ID
305370Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq
Other Designations
OTTHUMP00000023214|erythroid potentiating activity|fibroblast collagenase inhibitor|tissue inhibitor of metalloproteinase 1
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