TEK (Human) ELISA Kit
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Specification
Product Description
TEK (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human TIE2 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Suitable Sample
Cell culture supernates, cell lysates, serum and plasma (heparin, EDTA)
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
156 to 10000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — TEK
Entrez GeneID
7010Gene Name
TEK
Gene Alias
CD202B, TIE-2, TIE2, VMCM, VMCM1
Gene Description
TEK tyrosine kinase, endothelial
Gene Ontology
HyperlinkGene Summary
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq
Other Designations
OTTHUMP00000021167|soluble TIE2 variant 1|soluble TIE2 variant 2
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