IL4 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human IL4 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Calibration Range:
15.6 to 1000 pg/mL
Reactivity:
Human
Quality Control Testing:
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction:
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq