WWOX (Human) Cell-Based ELISA Kit
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Specification
Product Description
WWOX (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of WWOX expression in cultured cells.
Suitable Sample
Adherent cells, Suspension cells and Loosely attached cells
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human
Regulatory Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — WWOX
Entrez GeneID
51741Gene Name
WWOX
Gene Alias
D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1
Gene Description
WW domain containing oxidoreductase
Gene Ontology
HyperlinkGene Summary
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq
Other Designations
WW domain-containing oxidoreductase|WW domain-containing protein WWOX|fragile 16D oxido reductase|fragile site FRA16D oxidoreductase|putative oxidoreductase|short chain dehydrogenase/reductase family 41C, member 1
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