DCTN2 (Human) Cell-Based ELISA Kit
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Specification
Product Description
DCTN2 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of p50 Dynamitin expression in cultured cells.
Suitable Sample
Attached cell, loosely attached cell and suspension cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulatory Status
For research use only (RUO)
Storage Instruction
Store at 4°C for six months.
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Applications
Qualitative
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Gene Info — DCTN2
Entrez GeneID
10540Protein Accession#
Q13561Gene Name
DCTN2
Gene Alias
DCTN50, DYNAMITIN, RBP50
Gene Description
dynactin 2 (p50)
Omim ID
607376Gene Ontology
HyperlinkGene Summary
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq
Other Designations
50 kD dynein-associated polypeptide|dynactin 2|dynactin complex 50 kD subunit
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