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Last updated: 2019/8/12

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STK3/STK4 (Human) Cell-Based ELISA Kit 

  • Catalog # : KA5638
  • Visit Frequency :
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  • Specification
  • Product Description:
  • STK3/STK4 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of Mst1/2 expression in cultured cells.
  • Reactivity:
  • Human, Mouse
  • Storage Instruction:
  • Store at 4°C for six months.
  • Suitable Sample:
  • Attached cell, loosely attached cell and suspension cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulatory Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 6788
  • Protein Accession#:
  • Q13188; Q13043
  • Gene Name:
  • STK3
  • Gene Alias:
  • FLJ90748,KRS1,MST2
  • Gene Description:
  • serine/threonine kinase 3 (STE20 homolog, yeast)
  • Gene Summary:
  • Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM
  • Other Designations:
  • serine/threonine kinase 3 (Ste20, yeast homolog)
  • Gene Information
  • Entrez GeneID:
  • 6789
  • Protein Accession#:
  • Q13188; Q13043
  • Gene Name:
  • STK4
  • Gene Alias:
  • DKFZp686A2068,KRS2,MST1,YSK3
  • Gene Description:
  • serine/threonine kinase 4
  • Gene Summary:
  • The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000043418,dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)),kinase responsive to stress 2,mammalian sterile 20-like 1,yeast Ste20-like
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