PRKD1/PRKD2/PRKD3 (Human) Cell-Based ELISA Kit
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Specification
Product Description
PRKD1/PRKD2/PRKD3 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of PRKD1/PRKD2/PRKD3 expression in cultured cells.
Suitable Sample
Adherent cells, Suspension cells and Loosely attached cells
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human
Regulatory Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — PRKD1
Entrez GeneID
5587Gene Name
PRKD1
Gene Alias
PKC-MU, PKCM, PKD, PRKCM
Gene Description
protein kinase D1
Omim ID
605435Gene Ontology
HyperlinkGene Summary
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM
Other Designations
protein kinase C, mu
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Gene Info — PRKD3
Entrez GeneID
23683Gene Name
PRKD3
Gene Alias
EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU
Gene Description
protein kinase D3
Omim ID
607077Gene Ontology
HyperlinkGene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq
Other Designations
OTTHUMP00000126953|protein kinase C, nu|protein kinase EPK2|protein-serine/threonine kinase
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Gene Info — PRKD2
Entrez GeneID
25865Gene Name
PRKD2
Gene Alias
HSPC187, PKD2
Gene Description
protein kinase D2
Omim ID
607074Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
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