DAND5 (Human) ELISA Kit
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Specification
Product Description
DAND5 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for the quantitative measurement of human DAND5.
Suitable Sample
Cell Culture Supernates, Plasma (EDTA, Heparin) and Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
62.5 to 4000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — DAND5
Entrez GeneID
199699Protein Accession#
Q8N907Gene Name
DAND5
Gene Alias
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, MGC126849, SP1
Gene Description
DAN domain family, member 5
Omim ID
609068Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq
Other Designations
cerberus 2|cerberus-like 2|cysteine knot superfamily 1, BMP antagonist 3|dante
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