RLN3 (Human) ELISA Kit
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
RLN3 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human Relaxin 3 in cell culture supernates, serum and plasma (heparin).
Suitable Sample
Cell culture supernates, serum and plasma (heparin)
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
31.2 to 2000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for six months. For long term storage store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Quantification
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Gene Info — RLN3
Entrez GeneID
117579Gene Name
RLN3
Gene Alias
H3, RXN3, ZINS4, insl7
Gene Description
relaxin 3
Omim ID
606855Gene Ontology
HyperlinkGene Summary
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes. [provided by RefSeq
Other Designations
insulin-like 7
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Interactome
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Disease
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Publication Reference
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H3 relaxin protects against calcium oxalate crystal-induced renal inflammatory pyroptosis.
Jiannan Liu, Kelaier Yang, Yinshan Jin, Yadong Liu, Yaodong Chen, Xiaohui Zhang, Shiliang Yu, Erlin Song, Song Chen, Jingbo Zhang, Guanhua Jing, Ruihua An.
Cell proliferation 2020 Oct; 53(10):e12902.
Application：Quant, Human, Human serum.
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H3 relaxin protects against calcium oxalate crystal-induced renal inflammatory pyroptosis.
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