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Last updated: 2017/12/10

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UMOD (Human) ELISA Kit

  • Catalog # : KA4766
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  • Specification
  • Product Description:
  • UMOD (Human) ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of human UMOD.
  • Calibration Range:
  • 40.96 to 10000 pg/mL
  • Limit of Detection:
  • 40 pg/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA4766
    The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store the kit at-20°C.
  • Suitable Sample:
  • Serum, Plasma, Cell Culture Supernatants
  • Sample Volume:
  • 100 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 7369
  • Gene Name:
  • UMOD
  • Gene Alias:
  • ADMCKD2,FJHN,HNFJ,MCKD2,THGP,THP
  • Gene Description:
  • uromodulin
  • Gene Summary:
  • This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162212,Tamm-Horsfall glycoprotein,uromodulin (uromucoid, Tamm-Horsfall glycoprotein),uromucoid
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