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RPS6KB1 (pT421/S424)/Pan RPS6KB1 (Human/Mouse/Rat) ELISA Kit

  • Catalog # : KA4633
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  • Specification
  • Product Description:
  • RPS6KB1 (pT421/S424)/Pan RPS6KB1 (Human/Mouse/Rat) ELISA Kit is an enzyme-linked immunosorbent assay for qualitative determination of human, mouse, rat phospho RPS6KB1 (T421/S424) and Pan RPS6KB1.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at-20°C.
  • Suitable Sample:
  • Cell Lysate, Tissue Lysate
  • Sample Volume:
  • 100 uL
  • Label:
  • HRP-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 6198
  • Gene Name:
  • RPS6KB1
  • Gene Alias:
  • PS6K,S6K,S6K1,STK14A,p70(S6K)-alpha,p70-S6K,p70-alpha
  • Gene Description:
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq
  • Other Designations:
  • p70 S6 kinase, alpha 1,p70 S6 kinase, alpha 2,ribosomal protein S6 kinase, 70kD, polypeptide 1,serine/threonine kinase 14 alpha
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