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NFKBIA (pS32) (Human) ELISA Kit

  • Catalog # : KA4608
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  • Specification
  • Product Description:
  • NFKBIA (pS32) (Human) ELISA Kit is an enzyme-linked immunosorbent assay for qualitative determination of human phospho NFKBIA (S32).
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store the kit at-20°C.
  • Suitable Sample:
  • Cell Lysate, Tissue Lysate
  • Sample Volume:
  • 100 uL
  • Label:
  • HRP-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 4792
  • Gene Name:
  • NFKBIA
  • Gene Alias:
  • IKBA,MAD-3,NFKBI
  • Gene Description:
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • Gene Summary:
  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
  • Other Designations:
  • IkappaBalpha,nuclear factor of kappa light chain gene enhancer in B-cells
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