Progranulin (Human) ELISA Kit
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The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
Progranulin (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human Progranulin.
Suitable Sample
Cell culture supernatant, Plasma, Serum
Sample Volume
100 uL
Label
HRP-conjugate
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
62.5 to 4000 pg/mL
Limit of Detection
20.4 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C. Do not expose reagents to excessive light.
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Applications
Quantification
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Gene Info — GRN
Entrez GeneID
2896Gene Name
GRN
Gene Alias
GEP, GP88, PCDGF, PEPI, PGRN
Gene Description
granulin
Gene Ontology
HyperlinkGene Summary
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq
Other Designations
PC cell-derived growth factor|acrogranin|granulin-epithelin|proepithelin|progranulin
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Interactome
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Disease
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