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CFI (Human) ELISA Kit

  • Catalog # : KA4506
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  • Specification
  • Product Description:
  • CFI (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CFI.
  • Calibration Range:
  • 0.375 to 24 ug/mL
  • Limit of Detection:
  • 0.35 ug/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA4506
    The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store the kit at -20°C. For best results, please store the components as described in the protocol.
    Avoid repeated freezing and thawing.
  • Suitable Sample:
  • Cell culture supernatant, Milk, Plasma, Saliva, Serum
  • Sample Volume:
  • 25 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 3426
  • Gene Name:
  • CFI
  • Gene Alias:
  • C3B-INA,FI,IF,KAF
  • Gene Description:
  • complement factor I
  • Gene Summary:
  • This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq
  • Other Designations:
  • C3B/C4B inactivator,C3b-inactivator,I factor (complement),Konglutinogen-activating factor,complement component I,complement control protein factor I,light chain of factor I
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