ADAMTS4 (Human) ELISA Kit
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Specifications
Product Description
ADAMTS4 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human ADAMTS4.
Suitable Sample
Cell culture supernates, Cell Lysates, Plasma (heparin, EDTA), Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
625 to 40,000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — ADAMTS4
Entrez GeneID
9507Gene Name
ADAMTS4
Gene Alias
ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 4
Omim ID
603876Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
Other Designations
OTTHUMP00000032249|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4|aggrecanase-1
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