CAMKK2 Assay Kit is used for the measurement of the activities of purified or recombinant CAMKK22. Additionally, any cultured primary cell, cell line, or tissue can be assayed for CAMKK2 activity with the CAMKK2 Assay Kit if the appropriate dose of CAMKK2 specific inhibitor e.g. STO-609 is used.
Quality Control Testing:
Dose dependent curve
Dose dependency of recombinant CAMKK2.
Store the kit at 4°C. Do not expose reagents to excessive light.
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq
CAMKK beta protein,calcium/calmodulin-dependent protein kinase beta,calcium/calmodulin-dependent protein kinase kinase 2 beta