SIRT6 Deacetylase Fluorometric (Human) Assay Kit
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More Files
- More Functions
Dose dependent curve of recombinant SIRT6 activity.
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Specification
Product Description
SIRT6 Deacetylase Fluorometric (Human) Assay Kit is designed for the rapid and sensitive detection of deacetylase activity of recombinant SIRT6 and evaluation of SIRT6 inhibitors or activators using crude SIRT6 fraction or purified SIRT6.
Regulation Status
For research use only (RUO)
Quality Control Testing
Dose dependent curve
Dose dependent curve of recombinant SIRT6 activity.
Storage Instruction
Store the kit at -80°C. Do not expose reagents to excessive light.
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Applications
Functional Study
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Gene Info — SIRT6
Entrez GeneID
51548Gene Name
SIRT6
Gene Alias
SIR2L6
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
Omim ID
606211Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
sir2-related protein type 6|sirtuin 6|sirtuin type 6
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