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WISP1 (Human) ELISA Kit

  • Catalog # : KA4255
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  • Specification
  • Product Description:
  • WISP1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human WISP1.
  • Calibration Range:
  • 31.2 to 2000 pg/mL
  • Limit of Detection:
  • < 10 pg/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA4255
    The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store the kit at -20°C.
  • Suitable Sample:
  • Cell culture supernates, Plasma (EDTA, heparin) and Serum
  • Sample Volume:
  • 100 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 8840
  • Gene Name:
  • WISP1
  • Gene Alias:
  • CCN4,WISP1c,WISP1i,WISP1tc
  • Gene Description:
  • WNT1 inducible signaling pathway protein 1
  • Gene Summary:
  • This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq
  • Other Designations:
  • WNT1 induced secreted protein 1,Wnt-1 inducible signaling pathway protein 1,wnt-1 signaling pathway protein 1
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