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Last updated: 2017/7/23

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MMP12 (Human) ELISA Kit

  • Catalog # : KA4053
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  • Specification
  • Product Description:
  • MMP12 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human MMP12.
  • Calibration Range:
  • 62.5 to 4000 pg/mL
  • Limit of Detection:
  • <10 pg/mL
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store the kit at -20°C.
  • Suitable Sample:
  • Cell culture supernates, Plasma (heparin), Serum
  • Sample Volume:
  • 100 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 4321
  • Gene Name:
  • MMP12
  • Gene Alias:
  • HME,MGC138506,MME
  • Gene Description:
  • matrix metallopeptidase 12 (macrophage elastase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
  • Other Designations:
  • macrophage elastase,macrophage metalloelastase,matrix metalloproteinase 12,matrix metalloproteinase 12 (macrophage elastase)
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