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Last updated: 2019/12/8

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KLKB1 (Human) ELISA Kit 

  • Catalog # : KA3830
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  • Specification
  • Product Description:
  • KLKB1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human KLKB1.
  • Calibration Range:
  • 1.25 to 80.0 ng/mL
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Cell Culture Supernatant, CSF, Milk, Plasma, Saliva, Serum
  • Sample Volume:
  • 50 uL
  • Label:
  • Peroxidase-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 3818
  • Gene Name:
  • KLKB1
  • Gene Alias:
  • KLK3,PPK
  • Gene Description:
  • kallikrein B, plasma (Fletcher factor) 1
  • Gene Summary:
  • Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq
  • Other Designations:
  • Kallikrein, plasma,kallikrein 3, plasma,kallikrein B plasma,kininogenin,plasma kallikrein B1
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