CFH (Human) ELISA Kit
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Specification
Product Description
CFH (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CFH.
Suitable Sample
Cell Culture sample, CSF, Milk, Plasma, Saliva, Serum, Urine
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.281 to 18 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — CFH
Entrez GeneID
3075Gene Name
CFH
Gene Alias
ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS, MGC88246
Gene Description
complement factor H
Gene Ontology
HyperlinkGene Summary
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
H factor 1 (complement)|H factor 2 (complement)|OTTHUMP00000033598|age-related maculopathy susceptibility 1|beta-1-H-globulin|beta-1H|complement factor H, isoform b|factor H|factor H-like 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Activation of the classical complement pathway in myasthenia gravis with acetylcholine receptor antibodies.
Yukiko Ozawa, Akiyuki Uzawa, Yosuke Onishi, Manato Yasuda, Yuta Kojima, Satoshi Kuwabara.
Muscle & Nerve 2023 Nov; 68(5):798.
Application:ELISA, Human, Human serum.
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Activation of the classical complement pathway in myasthenia gravis with acetylcholine receptor antibodies.
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