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CFB (Human) ELISA Kit

  • Catalog # : KA3816
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  • Specification
  • Product Description:
  • CFB (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CFB.
  • Calibration Range:
  • 4.375 to 280 ng/mL
  • Limit of Detection:
  • 3.9 ng/mL
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve

    QC Testing of KA3816
    The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
  • Storage Instruction:
  • Store components of the kit at 4°C or -20°C as described in the protocol.
  • Suitable Sample:
  • Cell Culture Samples, CSF, Milk, Plasma, Saliva, Serum
  • Sample Volume:
  • 50 uL
  • Label:
  • Biotin-conjugate
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Publication Reference
  • 2.
  • Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
    Jiang K, Ma XP, Yu H, Cao G, Ding DL, Chen H, Huang HX, Gao YZ, Wu XP, Long XD, Zhang H, Zhang Y, Gao Y, Chen TY, Ren WH, Zhang P, Shi Z, Jiang W, Wan B, Saiyin H, Yin J, Zhou YF, Zhai Y, Lu PX, Zhang H, Gu X, Tan A, Wang JB, Zuo XB, Sun LD, Liu JO, Yi Q, Mo Z, Zhou G, Liu Y, Sun J, Shugart YY, Zheng SL, Zhang XJ, Xu J, Yu LHepatology. 2015 Mar 20. doi: 10.1002/hep.27794.
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 629
  • Gene Name:
  • CFB
  • Gene Alias:
  • BF,BFD,CFAB,FB,FBI12,GBG,H2-Bf,PBF2
  • Gene Description:
  • complement factor B
  • Gene Summary:
  • This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq
  • Other Designations:
  • B-factor, properdin,C3 proaccelerator,C3 proactivator,C3/C5 convertase,OTTHUMP00000029283,OTTHUMP00000174690,glycine-rich beta-glycoprotein
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