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SMC1A (Human) Cell-Based ELISA Kit

  • Catalog # : KA3560
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  • Specification
  • Product Description:
  • SMC1A (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of SMC1A expression in cultured cells.
  • Reactivity:
  • Human, Mouse
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 8243
  • Gene Name:
  • SMC1A
  • Gene Alias:
  • CDLS2,DKFZp686L19178,DXS423E,KIAA0178,MGC138332,SB1.8,SMC1,SMC1L1,SMC1alpha,SMCB
  • Gene Description:
  • structural maintenance of chromosomes 1A
  • Gene Summary:
  • Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000061876,SMC1 (structural maintenance of chromosomes 1, yeast)-like 1,SMC1 structural maintenance of chromosomes 1-like 1,segregation of mitotic chromosomes 1
  • Gene Pathway
  • Related Disease
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