VDR (Human) Cell-Based ELISA Kit
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Specification
Product Description
VDR (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of VDR expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — VDR
Entrez GeneID
7421Gene Name
VDR
Gene Alias
NR1I1
Gene Description
vitamin D (1,25- dihydroxyvitamin D3) receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
vitamin D (1,25-dihydroxyvitamin D3) receptor
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Interactome
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Disease
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