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Last updated: 2017/4/23

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VAV1 (Human) Cell-Based ELISA Kit

  • Catalog # : KA3545
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  • Specification
  • Product Description:
  • VAV1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of VAV1 expression in cultured cells.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 7409
  • Gene Name:
  • VAV1
  • Gene Alias:
  • VAV
  • Gene Description:
  • vav 1 guanine nucleotide exchange factor
  • Gene Summary:
  • The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq
  • Other Designations:
  • oncogene vav,vav 1 oncogene,vav proto-oncogene
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