TEK (Human) Cell-Based ELISA Kit
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Specification
Product Description
TEK (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of TEK expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — TEK
Entrez GeneID
7010Gene Name
TEK
Gene Alias
CD202B, TIE-2, TIE2, VMCM, VMCM1
Gene Description
TEK tyrosine kinase, endothelial
Gene Ontology
HyperlinkGene Summary
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq
Other Designations
OTTHUMP00000021167|soluble TIE2 variant 1|soluble TIE2 variant 2
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