COL18A1 (Human) ELISA Kit
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Specification
Product Description
COL18A1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human COL18A1.
Suitable Sample
Cell Culture Supernate, Human Milk, Plasma (EDTA, Heparin), Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
156 to 10,000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — COL18A1
Entrez GeneID
80781Gene Name
COL18A1
Gene Alias
FLJ27325, FLJ34914, KNO, KNO1, MGC74745
Gene Description
collagen, type XVIII, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000115472|OTTHUMP00000115473|alpha 1 type XVIII collagen|antiangiogenic agent|endostatin|multi-functional protein MFP
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