DOK1 (Human) Cell-Based ELISA Kit
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Specification
Product Description
DOK1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of DOK1 expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — DOK1
Entrez GeneID
1796Gene Name
DOK1
Gene Alias
MGC117395, MGC138860, P62DOK
Gene Description
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Omim ID
602919Gene Ontology
HyperlinkGene Summary
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq
Other Designations
Downstream of tyrosine kinase 1|docking protein 1|docking protein 1 (downstream of tyrosine kinase 1)|docking protein 1, 62kD (downstream of tyrosine kinase 1)
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