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GRM8 (Human) Cell-Based ELISA Kit

  • Catalog # : KA2996
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  • Specification
  • Product Description:
  • GRM8 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of GRM8 expression in cultured cells.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 2918
  • Gene Name:
  • GRM8
  • Gene Alias:
  • FLJ41058,GLUR8,GPRC1H,MGC126724,MGLUR8,mGlu8
  • Gene Description:
  • glutamate receptor, metabotropic 8
  • Gene Summary:
  • L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024506,glutamate metabotropic receptor 8
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