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GAD1 (Human) Cell-Based ELISA Kit

  • Catalog # : KA2880
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  • Specification
  • Product Description:
  • GAD1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of GAD1 expression in cultured cells.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 2571
  • Gene Name:
  • GAD1
  • Gene Alias:
  • FLJ45882,GAD,SCP
  • Gene Description:
  • glutamate decarboxylase 1 (brain, 67kDa)
  • Gene Summary:
  • This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000041055,glutamate decarboxylase 1,glutamate decarboxylase 1 (brain, 67kD)
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