HDAC5/HDAC9 (Human) Cell-Based ELISA Kit
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Specification
Product Description
HDAC5/HDAC9 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of HDAC5/HDAC9 expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — HDAC9
Entrez GeneID
9734Protein Accession#
Q9UQL6 (Gene ID : 10013);Q9UKV0 (Gene ID : 9734)Gene Name
HDAC9
Gene Alias
DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR
Gene Description
histone deacetylase 9
Omim ID
606543Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq
Other Designations
MEF-2 interacting transcription repressor (MITR) protein|histone deacetylase 4/5-related protein|histone deacetylase 7|histone deacetylase 7B
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Gene Info — HDAC5
Entrez GeneID
10014Protein Accession#
Q9UQL6 (Gene ID : 10013);Q9UKV0 (Gene ID : 9734)Gene Name
HDAC5
Gene Alias
FLJ90614, HD5, NY-CO-9
Gene Description
histone deacetylase 5
Omim ID
605315Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
antigen NY-CO-9
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Interactome
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Disease
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