PLA2G4A (Human) Cell-Based ELISA Kit
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Specification
Product Description
PLA2G4A (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of PLA2G4A expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — PLA2G4A
Entrez GeneID
5321Protein Accession#
P47712Gene Name
PLA2G4A
Gene Alias
MGC126350, PLA2G4, cPLA2-alpha
Gene Description
phospholipase A2, group IVA (cytosolic, calcium-dependent)
Omim ID
600522Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq
Other Designations
OTTHUMP00000033543|calcium-dependent phospholipid-binding protein|cytosolic phospholipase A2, group IVA|lysophospholipase|phosphatidylcholine 2-acylhydrolase
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