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COL1A2 (Human) Cell-Based ELISA Kit

  • Catalog # : KA2686
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  • Specification
  • Product Description:
  • COL1A2 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of COL1A2 expression in cultured cells.
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 1278
  • Gene Name:
  • COL1A2
  • Gene Alias:
  • OI4
  • Gene Description:
  • collagen, type I, alpha 2
  • Gene Summary:
  • This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
  • Other Designations:
  • alpha 2 type I collagen,alpha 2(I)-collagen,alpha-2 collagen type I,collagen I, alpha-2 polypeptide,collagen of skin, tendon and bone, alpha-2 chain,type I procollagen
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