CFL1/CFL2 (Human) Cell-Based ELISA Kit
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Specification
Product Description
CFL1/CFL2 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of CFL1/CFL2 expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — CFL1
Entrez GeneID
1072Protein Accession#
P23528 (Gene ID : 1073);Q9Y281 (Gene ID : 1072)Gene Name
CFL1
Gene Alias
CFL
Gene Description
cofilin 1 (non-muscle)
Omim ID
601442Gene Ontology
HyperlinkGene Summary
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM
Other Designations
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Gene Info — CFL2
Entrez GeneID
1073Protein Accession#
P23528 (Gene ID : 1073);Q9Y281 (Gene ID : 1072)Gene Name
CFL2
Gene Alias
NEM7
Gene Description
cofilin 2 (muscle)
Gene Ontology
HyperlinkGene Summary
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
cofilin 2
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Interactome
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Pathway
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Disease
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