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CCR5 (Human) Cell-Based ELISA Kit

  • Catalog # : KA2647
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  • Specification
  • Product Description:
  • CCR5 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of CCR5 expression in cultured cells.
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 1234
  • Gene Name:
  • CCR5
  • Gene Alias:
  • CC-CKR-5,CCCKR5,CD195,CKR-5,CKR5,CMKBR5,IDDM22
  • Gene Description:
  • chemokine (C-C motif) receptor 5
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • C-C chemokine receptor 5,C-C chemokine receptor type 5,CCR5 chemokine receptor,chemokine (C-C) receptor 5,chemokine receptor CCR5,chemr13
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