CASR (Human) Cell-Based ELISA Kit
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Specification
Product Description
CASR (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of CASR expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — CASR
Entrez GeneID
846Protein Accession#
P41180Gene Name
CASR
Gene Alias
CAR, FHH, FIH, GPRC2A, HHC, HHC1, MGC138441, NSHPT, PCAR1
Gene Description
calcium-sensing receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq
Other Designations
extracellular calcium-sensing receptor|parathyroid Ca(2+)-sensing receptor 1
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