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CDH1/CDH2/CDH3/CDH4 (Human) Cell-Based ELISA Kit

  • Catalog # : KA2621
  • Visit Frequency :
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  • Specification
  • Product Description:
  • CDH1/CDH2/CDH3/CDH4 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of CDH1/CDH2/CDH3/CDH4 expression in cultured cells.
  • Reactivity:
  • Human, Mouse, Rat
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Attached Cell, Loosely Attached Cell, Suspension Cell
  • Label:
  • HRP-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Qualitative
  • Application Image
  • Qualitative
  • Gene Information
  • Entrez GeneID:
  • 999
  • Protein Accession#:
  • P12830 (Gene ID : 999);P19022 (Gene ID : 1000);P22223 (Gene ID : 1001);P55283 (Gene ID : 1002)
  • Gene Name:
  • CDH1
  • Gene Alias:
  • Arc-1,CD324,CDHE,ECAD,LCAM,UVO
  • Gene Description:
  • cadherin 1, type 1, E-cadherin (epithelial)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq
  • Other Designations:
  • cadherin 1, E-cadherin (epithelial),cadherin 1, type 1,calcium-dependent adhesion protein, epithelial,cell-CAM 120/80,uvomorulin
  • Gene Information
  • Entrez GeneID:
  • 1000
  • Protein Accession#:
  • P12830 (Gene ID : 999);P19022 (Gene ID : 1000);P22223 (Gene ID : 1001);P55283 (Gene ID : 1002)
  • Gene Name:
  • CDH2
  • Gene Alias:
  • CD325,CDHN,CDw325,NCAD
  • Gene Description:
  • cadherin 2, type 1, N-cadherin (neuronal)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq
  • Other Designations:
  • N-cadherin 1,cadherin 2, N-cadherin (neuronal),cadherin 2, type 1,calcium-dependent adhesion protein, neuronal,neural cadherin
  • Gene Information
  • Entrez GeneID:
  • 1001
  • Protein Accession#:
  • P12830 (Gene ID : 999);P19022 (Gene ID : 1000);P22223 (Gene ID : 1001);P55283 (Gene ID : 1002)
  • Gene Name:
  • CDH3
  • Gene Alias:
  • CDHP,HJMD,PCAD
  • Gene Description:
  • cadherin 3, type 1, P-cadherin (placental)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq
  • Other Designations:
  • cadherin 3, type 1,calcium-dependent adhesion protein, placental
  • Gene Information
  • Entrez GeneID:
  • 1002
  • Protein Accession#:
  • P12830 (Gene ID : 999);P19022 (Gene ID : 1000);P22223 (Gene ID : 1001);P55283 (Gene ID : 1002)
  • Gene Name:
  • CDH4
  • Gene Alias:
  • CAD4,FLJ22202,FLJ40547,MGC126700,MGC138355,RCAD
  • Gene Description:
  • cadherin 4, type 1, R-cadherin (retinal)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031444,R-cadherin,cadherin 4, type 1,cadherin 4, type 1, preproprotein,retinal cadherin
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